Emotionally Unstable Personality Disorder (EUPD), often referred to as Borderline Personality Disorder (BPD), impacts social interactions, emotional stability, and may lead to impulsive or self-harming actions. Treatment expenses can be significant, with efficacy rates between 35% and 50%. Researchers are investigating alternative therapies to supplement conventional treatments.
A notable potential addition to EUPD management is cannabis, commonly known as weed. It’s budget-friendly, and its components may provide advantages for individuals with EUPD. Those facing financial constraints might consider cheap cannabis online options for more affordable solutions.
Table of Contents
Key Takeaways:
- Individuals with EUPD who use THC or high CBD report positive outcomes in symptom management.
- High doses of CBD (800 mg/day) and THC flower can elevate circulating anandamide levels.
- Dysfunction in the endocannabinoid system, which regulates emotions and stress, plays a role in Emotionally Unstable Personality Disorder.
Understanding EUPD or BPD
EUPD is a mental health disorder that influences self-perception and interpersonal relationships, leading to challenges in daily functioning. It is characterized by intense, unstable relationships, impulsivity, and distorted self-image.
The precise causes remain unclear, but factors like genetics, trauma, and neurotransmitter imbalances could contribute. Dysfunction in the endocannabinoid system may also exacerbate EUPD symptoms.
EUPD Treatment
Despite guidelines indicating no medications effectively treat EUPD, healthcare providers may prescribe drugs such as antipsychotics and antidepressants.
Antipsychotic and sedative medications can assist in short-term crisis management or treating co-occurring disorders. Reports suggest up to 90% of EUPD patients use at least one psychotropic medication, which may include antipsychotics, antidepressants, mood stabilizers, and sedatives.
Polypharmacy is prevalent in this population, with many medications carrying side effects and being used off-label. While certain drugs might alleviate specific symptoms, they do not alter the overall prognosis of the disorder.
Cannabis-Based Medicine for EUPD (CBM)
Cannabis-based medicines are derived from the cannabis plant and contain cannabinoids, the active compounds like tetrahydrocannabinol (THC) and cannabidiol (CBD). These products can address medical conditions, including pain, inflammation, anxiety, and seizures.
Numerous studies are examining the mental health impacts. Research published in Frontiers in Psychiatry suggests marijuana may mitigate depression and improve sleep quality and overall well-being. Such findings warrant further exploration into marijuana’s effects on various mental health disorders.
CBM for Unstable Personality Disorder
A narrative review and case series from 2022 emphasized cannabinoid use in managing EUPD symptoms among seven patients. The researchers investigate cellular and molecular mechanisms and evaluate current evidence for cannabis-based medicinal products (CBMP) as a possible EUPD treatment.
Materials and Methods
Participants diagnosed with EUPD had previously tried at least one medication and one psychotherapy type, with a follow-up review at a Zerenia clinic that included patient-reported outcome measures (PROMS) records.
CBM included dried flower for inhalation (20-60g monthly) and oral extracts with THC (9-10mg/day) and CBD (40mg/day). The formulations varied between high THC, balanced THC and CBD, and high CBD.
Measurements utilized the Clinical Global Impression Improvement (CGI-I) Scale (1-7) and the Patient’s Global Impression of Change (PGIC) Scale (1-7).
Researchers tailored dosages through gradual titration, offering guidelines for dose increases until satisfactory symptom control or side effects were observed.
Results
At one-month follow-up, six participants noted improvements, with five rating their change as a six on the PGIC scale. One patient receiving a chemotype 2 oral extract experienced no benefit, indicating that inhaled THC or higher oral CBD doses may be more effective.
All participants tolerated the treatment well, with no side effects reported, which is vital for adherence. Younger patients might find comfort in medical cannabis despite societal stigma.
Hypothesis
Researchers propose that exogenous cannabinoids may help restore the tonic activation of the endocannabinoid system (ECS) in the central nervous system (CNS). THC activates presynaptic CB1 receptors, while both cannabinoids bind to fatty-acid binding proteins (FABPs), potentially slowing anandamide deactivation.
High doses of oral CBD (800 mg/day) and patients using chemotype 1 flower exhibit elevated anandamide levels. It’s unclear whether this is due to CBD’s influence on anandamide transport or degradation or its interaction with other molecular targets. In contrast, psychiatric medications often take 2-3 weeks to show effects, with longer durations for patients to achieve remission.
Rapid symptom relief is critical during an “EUPD crisis,” as distressed patients may resort to benzodiazepines and other anxiety medications, which can cause rapid tolerance and dependence.
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Frequently Asked Questions
Does cheap marijuana have poor quality?
No, price is not the only determinant of product quality. Assess quality by examining the product’s physical traits and personal experience. Some dispensaries may offer lower prices during monthly or clearance sales. If a dispensary’s prices are significantly lower than the cannabis industry standard, it may raise quality concerns.
Does marijuana cause any adverse effects when managing BPD?
Marijuana has shown no adverse effects reported by study participants. This is crucial for medication adherence, as a review of 36 studies indicated that side effects accounted for 28% of patients’ non-adherence to antipsychotics. An unfavorable attitude toward antipsychotic medication was the second most common reason for intentional non-adherence, at 30.5%.
What is the quickest way to experience the effects of cannabinoids for an EUPD problem?
Smoking, vaping, and dabbing are the fastest methods to experience cannabinoid effects. Participants in the study used vaping to consume dried flower. While smoking and vaping yield similar effects, the distinction lies in the inhalation of smoke (from smoking) versus vapor (from vaping). Dabbing, involving concentrates, also provides a quick onset of effects.
How many times can I smoke or vape to manage my symptoms?
The effectiveness of cannabis strains and products depends on individual preferences. In the study, researchers permitted patients to adjust their daily dose (between 0.5 and 2 grams per day) without exceeding the monthly limit. For extracts, patients documented their daily dosage.
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